Pinching the outer skin layer can be quite painful. So your first instinct will be to reduce this pain. Applying a cold compress to the area makes it numb and reduces the pain. You can place an ice cube directly over the blisters for immediate effect. This will subside the pain and allow you to work on the blister.
If the pain does not go away with the cold compress, take a pain killer to get rid of it. Painkillers like acetaminophen (Tylenol) or ibuprofen (Motrin) can help you get relief. Antiviral gels can also be applied to the blisters to ease the pain and get rid of them.
The area with blisters gets very sensitive because it is a small wound. You have to avoid salty and spicy foods that irritates this area until the blister disappears. Avoid pickles and crackers during this period. Use of forks can also aggravate the blisters and pop them to bleed. Avoid anything that is pointed and can disturb the blisters. Eat soft foods instead of raw hard ones. Take a break from acidic juices like citrus and lime that can irritate the sensitive area.
Crush a small piece of garlic and place it on the blisters. Garlic not only helps in getting rid of the blisters but also discourages growth of any bacteria on them. It is a natural germ killer and very effective against herpes in the mouth. Another remedy you can use is to apply a slice of fresh ginger to the infected area. Ginger reduces inflammation and swelling and can soothe the blisters down.