The first thing is to evaluate your own needs. This can be a major factor in deciding the most suitable home job for you. Are you simply considering it on a part-time basis, or whether you want to take it to the next level by making a career out of it? By answering these simple questions, you will have a fair idea about the type of job you are looking for, which further matches your qualifications and experience. Additionally for most home-based employees, certifications may not play much of a part where you can easily pursue the area of interest.
Working as a content or a free-lance writer could be an option. There are various websites which pay writers fees depending on the numbers of articles they can write each day. Moreover, depending on the traffic, you can easily earn bonuses etc. E.g. include Constant Content, The Helium Market place etc.
Working for a call center is another viable source of making money from the comfort of your home. LiveOps and Alpine Access are legitimate companies which allow you do pursue the job from home where all you need to have is strong communication skills and grip on a foreign language.
If you can have a reasonable inventory, you can become an eBay seller, or earn money from Yahoo auctions. These websites allow you to interact with potential customers by posting your inventory. All you have to do is to set-up an account and you are good to go.
If you are good at teaching, you can easily start your own home tuition centre, charging hourly rates to students. On the other hand, you can even open up child care service on a small scale. Both services may be subject to licensing however.