Readers are generally connected to the USB-interface on the motherboard. It is better to know the technical documentation of your computer before installing the internal card reader. Disconnect power from the computer, remove the system cover and carefully read the board. Look for a USB interface connection according to the scheme of the motherboard of your computer. If you do not have motherboard circuit, locate the USB interface directly on the system board. This should not be a problem but it might take more time.
When the USB-interface is found, connect the power cord back and insert the card reader. Usually, an internal card reader is installed in the free space on the front panel of the computer. There is also a special section for the installation of additional equipment. To set it back, remove the cover on the front of the computer and insert the card reader in the chassis.
After the installation, do not hurry to close the system cover. Apply power to the computer and turn it on. Wait until the operating system loads. When the operating system is fully loaded, you will get a “found new hardware” message by the operating system and it it will further recommend you to download some of the drivers that are needed to help the device function properly. Wait until the end of this process, until you see "The device has successfully connected and ready to work."