How Levitra was Developed

So how was Levitra, one of the forerunners for erectile dysfunction developed? In Novelber of 2001 Bayer and GlaxoSmithKline signed a worldwide co-promotion and co-development agreement for Levitra. Levitra has received regulatory approval for the treatment of penile dsyfunction in more than sixty-three countries. Levitra was one of the first drugs for erectile dysfunction to hit the market with approval from the U.S. Food and Drug Administration in August 2003.

According to the Levitra website the chemical break down is as follows: monohydrochloride salt of vardenafil is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5).

Vardenafil HCl is designated chemically as piperazine, 1-[[3-(1,4-dihydro-5-methyl-4-oxo-7-propylimidazo[5,1-f ][1,2,4]triazin-2-yl)-4-ethoxyphenyl]sulfonyl]-4-ethyl-, monohydrochloride. Vardenafil HCl is a nearly colorless, solid substance with a molecular weight of 579.1 g/mol and a solubility of 0.11 mg/mL in water. LEVITRA is formulated as orange, round, film-coated tablets with “BAYER” cross debossed on one side and “2.5”, “5”, “10”, and “20” on the other side corresponding to 2.5 mg, 5 mg, 10 mg, and 20 mg of vardenafil, respectively. Each tablet contains microcrystalline cellulose, crospovidone, colloidal silicon dioxide, magnesium stearate, hypromellose, polyethylene glycol, titanium dioxide, yellow ferric oxide, and red ferric oxide.

Now for many readers most of this will be Greek but what it translates to is that today’s men are getting the best drug possible to help with penile dysfunction. It should be noted that Levitra is a prescription medicine that is used to treat erectile dysfunction and not any other medical condition. Men taking nitrate drugs, often used to control chest pain should not take Levitra. The starting dose of Levitra is 10 mg taken no more than once per day. In patients taking certain medications such as ritonavir, indinavir, ketoconazole, itraconazole, and erythromycin, lower doses of Levitra are recommended. It is important that you tell your doctor every medication that you are taking so that the determination can be made as to how much Levitra you should take and how often.

Levitra was developed for the sole purpose of addressing the issue of penile dysfunction which affects many men today. For a great many years men were embarrassed to step forward to admit they had this problem but once the drugs to correct it became available more men came forward to express their concerns about having this problem. The Bayer company, which has been a trusted name in pharmaceuticals for many years, decided to pursue creating a drug for penile dysfunction when information can forward about how many men are actually affected by this condition.

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